Myeloid-derived suppressor cells (MDSC) assessment using an automated sequential chromogenic multiplex assay (Brightplex®)

Brightplex MDSC

What's in the poster?

This poster was presented at the Society for Immunotherapy of Cancer (SITC) conference in 2018. This work will provide:

  • a background on the biology of myeloid-derived suppressor cells (MDSCs) in the context of non-small cell lung cancer (NSCLC)
  • a showcase of the Brightplex® MDSC multiplex IHC panel comprised of CD11b, CD14, CD15, HLA-DR, LOX1, and S100A9
  • phenotypic analysis strategies for tissue segmentation and quantifying cell densities of MDSC subtypes

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